Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etocarlide SCHEMBL7874588 | 0.90 | MAPT (0.68) | MAPTGAAKMT2AL3MBTL1ALDH1A1 | |
| Etocarlide SCHEMBL7865543 | 0.89 | MAPT (0.66) | MAPTGAAKMT2AL3MBTL1ALDH1A1 | |
| Etocarlide SCHEMBL7874742 | 0.89 | MAPT (0.66) | MAPTGAAKMT2AL3MBTL1ALDH1A1 | |
| Etocarlide SCHEMBL7865390 | 0.89 | MAPT (0.69) | MAPTGAAKMT2AL3MBTL1ALDH1A1 | |
| Etocarlide SCHEMBL2857287 | 0.89 | MAPT (0.73) | MAPTGAAKMT2AL3MBTL1ALDH1A1 | |
| Etocarlide SCHEMBL7874655 | 0.88 | MAPT (0.64) | MAPTGAAKMT2AL3MBTL1ALDH1A1 | |
| Etocarlide SCHEMBL7877294 | 0.88 | MAPT (0.64) | MAPTGAAKMT2AL3MBTL1ALDH1A1 | |
| Etocarlide SCHEMBL7871203 | 0.87 | MAPT (0.71) | MAPTGAAKMT2AL3MBTL1ALDH1A1 | |
| Etocarlide SCHEMBL7872876 | 0.87 | MAPT (0.71) | MAPTGAAKMT2AL3MBTL1ALDH1A1 | |
| Etocarlide SCHEMBL7877205 | 0.87 | MAPT (0.71) | MAPTGAAKMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316575-B1 | MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE | IDEMITSU KOSAN CO., LTD. (JP) | 2001-11-13 | — | — | US | claimed |