Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12317262 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 | |
| SCHEMBL31153658 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 | |
| SCHEMBL6457363 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 | |
| SCHEMBL1223254 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 | |
| SCHEMBL1727458 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 | |
| SCHEMBL31215222 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 | |
| SCHEMBL1223256 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 | |
| SCHEMBL1298114 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 | |
| SCHEMBL1298118 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 | |
| SCHEMBL1297678 | 1.00 | PPM1B (0.47) | PPM1BPTPN1PPP1CCCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136474-A2 | SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS | NOVARTIS AG (CH) | 2010-12-02 | — | — | WO | disclosed |