SCHEMBL7877470

SCHEMBL7877470

Cc1cccc(-c2ccccc2Nc2ccc(CCO)cc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.46
MEN1 O00255 3/20 0.46
LMNA P02545 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
MAPK1 P28482 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPKAPK2 P49137 1/20 0.46
HCAR2 Q8TDS4 1/20 0.42
ALDH1A1 P00352 2/20 0.42
PLA2G1B P04054 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
FFAR1 O14842 2/20 0.41
FFAR4 Q5NUL3 2/20 0.41
CDC7 O00311 1/20 0.40
ALK Q9UM73 1/20 0.40
PDE4B Q07343 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7871347 0.90 HCAR2 (0.39) L3MBTL1MEN1LMNAKMT2AMAPT
SCHEMBL7874942 0.88 HCAR2 (0.40) L3MBTL1MEN1LMNAKMT2AMAPT
SCHEMBL130522 0.83 NPSR1 (0.46) L3MBTL1MEN1LMNAKMT2AMAPT
SCHEMBL7871380 0.83 HCAR2 (0.37) L3MBTL1MEN1LMNAKMT2ANPC1
SCHEMBL17246941 0.81 NPSR1 (0.56) L3MBTL1MEN1LMNAKMT2AMAPT
SCHEMBL7871392 0.81 PDE4B (0.37) L3MBTL1MEN1LMNAKMT2ANPC1
SCHEMBL6081498 0.81 NPSR1 (0.41) L3MBTL1MEN1LMNAKMT2AMAPT
SCHEMBL1505781 0.80 NPSR1 (0.43) L3MBTL1MEN1LMNAKMT2AMAPT
SCHEMBL332285 0.80 NPSR1 (0.44) L3MBTL1MEN1LMNAKMT2AMAPT
SCHEMBL7865722 0.79 MAPT (0.44) L3MBTL1MEN1LMNAKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010017155-A1 Of monovinylated triarylamine monomers; use in light emitting diodes or as components of photorefractive materials CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-08-30 US disclosed