Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877624 | 0.88 | CDK1 (0.53) | CDK1GAATP53GLAMAPT | |
| SCHEMBL7877909 | 0.83 | CDK1 (0.51) | CDK1GAATP53GLAMAPT | |
| SCHEMBL9198868 | 0.80 | CDK1 (0.56) | CDK1GAATP53GLAMAPT | |
| SCHEMBL9198864 | 0.80 | CDK1 (0.56) | CDK1GAATP53GLAMAPT | |
| SCHEMBL7877614 | 0.79 | HPGD (0.51) | CDK1GAAMAPTMEN1KMT2A | |
| SCHEMBL7877627 | 0.79 | HPGD (0.51) | CDK1GAAMAPTMEN1KMT2A | |
| SCHEMBL8536414 | 0.79 | CDK1 (0.80) | CDK1GAATP53GLAMAPT | |
| SCHEMBL8782215 | 0.77 | CDK1 (0.62) | CDK1GAATP53GLAMAPT | |
| SCHEMBL5846414 | 0.77 | CDK1 (0.62) | CDK1GAATP53GLAMAPT | |
| SCHEMBL10396053 | 0.77 | CDK1 (0.62) | CDK1GAATP53GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331506-B1 | Disubstituted methylidene hydrazinophenyl sulfonylureas, process for their production and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 2001-12-18 | — | — | US | disclosed |