SCHEMBL7878207

SCHEMBL7878207

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr](Cc1ccccc1)(Cc1ccccc1)(C1C(C)=Cc2c(-c3ccccc3)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7886092 0.86 PDCD1 (0.30) PDCD1CD274
SCHEMBL5951833 0.86
SCHEMBL5004259 0.84
SCHEMBL796297 0.83 BCHE (0.31)
SCHEMBL7886951 0.81
SCHEMBL1130923 0.80 BRD4 (0.31) PDCD1CD274
SCHEMBL60641 0.80 PDCD1 (0.31) PDCD1CD274
SCHEMBL136348 0.79 PDCD1 (0.30) PDCD1CD274
SCHEMBL7909298 0.79 PDCD1 (0.30) PDCD1CD274
SCHEMBL7906393 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6177376-B1 REACTING METALLOCENE WITH ORGANOLITHIUM COMPOUND AND GRIGNARD COMPOUND, ACTIVATION, CONTACTING WITH SUPPORT TARGOR GMBH (DE) 2001-01-23 US disclosed