Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7884956 | 0.91 | PDE9A (0.81) | PDE9A | |
| SCHEMBL7876909 | 0.90 | PDE9A (1.00) | PDE9A | |
| SCHEMBL7886937 | 0.89 | PDE9A (1.00) | PDE9A | |
| SCHEMBL7882548 | 0.89 | PDE9A (1.00) | PDE9A | |
| SCHEMBL7876055 | 0.88 | PDE9A (0.84) | PDE9A | |
| SCHEMBL7882454 | 0.87 | PDE9A (1.00) | PDE9A | |
| SCHEMBL7886935 | 0.87 | PDE9A (1.00) | PDE9A | |
| SCHEMBL7882542 | 0.87 | PDE9A (1.00) | PDE9A | |
| SCHEMBL7877685 | 0.87 | PDE9A (1.00) | PDE9A | |
| SCHEMBL12399465 | 0.86 | PDE9A (0.82) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112437-A1 | 1-HETEROCYCLYL-1, 5-DIHYDRO-PYRAZOLO [3, 4-D] PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS PDE9A MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-07 | — | — | WO | disclosed |
| WO-2009121919-A1 | 1-HETEROCYCLYL-1,5-DIHYDRO-PYRAZOLO[3,4-D] PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS PDE9A MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-08 | — | — | WO | disclosed |