Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194954 | 1.00 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7879317 | 1.00 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4D | |
| Phthalimide SCHEMBL8054751 | 0.86 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7792760 | 0.83 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7792763 | 0.83 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7181659 | 0.79 | PDE4B (0.79) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7177924 | 0.79 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6172991 | 0.77 | PDE4B (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7375528 | 0.76 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7426818 | 0.75 | PDE4B (0.80) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172118-B1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2001-01-09 | — | — | US | disclosed |