Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696059 | 0.89 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL12774618 | 0.86 | MTOR (0.76) | MTORPIK3CA | |
| SCHEMBL7871332 | 0.86 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL6893222 | 0.82 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL7872389 | 0.82 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL7871335 | 0.80 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL7883176 | 0.80 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL7875319 | 0.80 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL693916 | 0.80 | MTOR (0.80) | MTOR | |
| SCHEMBL695185 | 0.79 | MTOR (0.75) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090564-B2 | 5-alkynyl-pyridines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2015-07-28 | — | — | US | disclosed |
| US-9090564-B2 | 5-alkynyl-pyridines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2015-07-28 | — | — | US | disclosed |
| US-20130196975-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-08-01 | — | — | US | disclosed |
| US-20130196975-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-08-01 | — | — | US | disclosed |
| US-20110098275-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196975-A1 | 5-ALKYNYL-PYRIDINES | MKI67, KIT, CCNA1 | MTOR 1220/4885PIK3CA 2480/4885 |
| US-20110098275-A1 | 5-ALKYNYL-PYRIDINES | MKI67, KIT, CCNA1 | MTOR 1220/4885PIK3CA 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.