Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586624 | 0.72 | ELANE (0.87) | ELANECYP2C19 | |
| SCHEMBL15866528 | 0.72 | ELANE (0.87) | ELANECYP2C19 | |
| SCHEMBL2117342 | 0.72 | ELANE (0.87) | ELANECYP2C19 | |
| SCHEMBL2631138 | 0.72 | ELANE (0.65) | ELANECYP2C19 | |
| SCHEMBL2116319 | 0.72 | ELANE (0.87) | ELANECYP2C19 | |
| SCHEMBL6315181 | 0.68 | MEN1 (0.49) | — | |
| SCHEMBL7391000 | 0.67 | ELANE (0.43) | ELANE | |
| SCHEMBL6314271 | 0.67 | TP53 (0.47) | CYP2C19 | |
| SCHEMBL6321503 | 0.67 | USP2 (0.57) | — | |
| SCHEMBL6312587 | 0.66 | MAPK1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010115548-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTITUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | WO | disclosed |