Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | CASP7 | P55210 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471684 | 0.84 | ATM (0.42) | ATMBRD4CCL2ALDH1A1MAPT | |
| SCHEMBL28925179 | 0.84 | ATM (0.42) | ATMBRD4CCL2ALDH1A1MAPT | |
| SCHEMBL28202894 | 0.73 | BRD4 (0.38) | ATMBRD4CCL2ALDH1A1MAPT | |
| SCHEMBL16245516 | 0.72 | BRD4 (0.38) | ATMBRD4CCL2ALDH1A1MAPT | |
| SCHEMBL31561672 | 0.69 | BRD4 (0.38) | ATMBRD4CCL2ALDH1A1MAPT | |
| SCHEMBL28153734 | 0.69 | BRD4 (0.38) | ATMBRD4CCL2ALDH1A1MAPT | |
| SCHEMBL28981690 | 0.69 | BRD4 (0.35) | ATMBRD4CCL2ALDH1A1MAPT | |
| SCHEMBL16469941 | 0.68 | BRD4 (0.37) | ATMBRD4CCL2ALDH1A1MAPT | |
| SCHEMBL1356607 | 0.68 | BRD4 (0.37) | ATMBRD4CCL2ALDH1A1MAPT | |
| SCHEMBL27573091 | 0.66 | MAPT (0.44) | ATMBRD4CCL2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319931-B1 | APOPTOSIS-INDUCING AGENT FOR CANCER TREATMENT | CENTRE NATIONAL DE AL RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-11-20 | — | — | US | disclosed |