Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.55 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16299641 | 0.99 | PDE5A (0.54) | PDE5ADPP4FAP | |
| SCHEMBL16299631 | 0.92 | PDE5A (0.46) | PDE5ADPP4FAP | |
| SCHEMBL10201590 | 0.92 | PDE5A (0.44) | PDE5ADPP4FAP | |
| SCHEMBL8360697 | 0.91 | PDE5A (0.51) | PDE5A | |
| SCHEMBL6683134 | 0.91 | PDE5A (0.55) | PDE5A | |
| SCHEMBL16312814 | 0.91 | PDE5A (0.44) | PDE5ADPP4FAP | |
| SCHEMBL8360079 | 0.91 | PDE5A (0.51) | PDE5A | |
| SCHEMBL10201565 | 0.90 | PDE5A (0.46) | PDE5ADPP4FAP | |
| SCHEMBL10201530 | 0.89 | PDE5A (0.44) | PDE5ADPP4FAP | |
| SCHEMBL10201556 | 0.89 | PDE5A (0.45) | PDE5ADPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020724-A1 | POLYCYCLIC GUANINE PHOSPHODIESTERASE V INHIBITORS | SCHERING CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |