Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504862 | 0.89 | GRM5 (0.72) | GRM5KCNH2 | |
| SCHEMBL504810 | 0.88 | GRM5 (0.68) | GRM5KCNH2 | |
| SCHEMBL505072 | 0.83 | GRM5 (0.71) | GRM5KCNH2 | |
| SCHEMBL504823 | 0.82 | GRM5 (0.63) | GRM5KCNH2 | |
| SCHEMBL10253715 | 0.82 | GRM5 (0.65) | GRM5KCNH2 | |
| SCHEMBL505228 | 0.81 | GRM5 (0.71) | GRM5KCNH2 | |
| SCHEMBL505324 | 0.81 | GRM5 (0.67) | GRM5KCNH2 | |
| SCHEMBL506040 | 0.80 | GRM5 (0.69) | GRM5KCNH2 | |
| SCHEMBL505420 | 0.80 | GRM5 (0.72) | GRM5KCNH2 | |
| SCHEMBL504752 | 0.80 | GRM5 (0.65) | GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114971-A1 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SEPRACOR INC. (US) | 2010-10-07 | — | — | WO | disclosed |