Hexachloroethane

Hexachloroethane

SCHEMBL788209

ClC(Cl)(Cl)C(Cl)(Cl)Cl.ClC(Cl)(Cl)C(Cl)(Cl)Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
CYP2E1 P05181 1/20 0.50
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexachloroethane SCHEMBL1330771 1.00
Hexachloroethane SCHEMBL23458 1.00
Hexachloroethane SCHEMBL28939673 0.91
Hexachloroethane SCHEMBL867041 0.91 TSHR (0.67) TSHRALDH1A1LMNACYP2E1THRB
Hexachloroethane SCHEMBL2273691 0.91
Hexachloroethane SCHEMBL34463651 0.91
Hexachloroethane SCHEMBL10480058 0.91
Hexachloroethane SCHEMBL28924275 0.91
Hexachloroethane SCHEMBL11301187 0.84 TSHR (0.44) TSHRALDH1A1LMNACYP2E1THRB
Hexachloroethane SCHEMBL11881487 0.79 TSHR (0.75) TSHRALDH1A1LMNACYP2E1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104292069-B A kind of preparation method of zellon TECHNOLOGY CENTER OF JUHUA GROUP (CN) 2016-01-13 CN disclosed
CN-104292069-A Tetrachloroethylene preparation method JUHUA GROUP TECHNOLOGY CT 2015-01-21 CN disclosed
EP-2616484-A2 SCREENING METHOD Universiteit Leiden (NL) 2013-07-24 EP disclosed
WO-2012035120-A2 SCREENING METHOD UNIVERSITEIT LEIDEN (NL) 2012-03-22 WO disclosed
US-5600958-A Shipper HENNING STEVE (US) 1997-02-11 US disclosed