Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15866539 | 0.91 | ELANE (0.56) | ELANECYP2C9CYP2C19 | |
| SCHEMBL2117972 | 0.89 | ELANE (0.72) | ELANECYP2C9CYP2C19 | |
| SCHEMBL2631132 | 0.84 | ELANE (0.63) | ELANECYP2C9CYP2C19 | |
| SCHEMBL2631138 | 0.83 | ELANE (0.65) | ELANECYP2C9CYP2C19 | |
| SCHEMBL15473114 | 0.82 | ELANE (0.61) | ELANECYP2C9CYP2C19 | |
| SCHEMBL15473108 | 0.82 | ELANE (0.61) | ELANECYP2C9CYP2C19 | |
| SCHEMBL15473056 | 0.82 | ELANE (0.61) | ELANECYP2C9CYP2C19 | |
| SCHEMBL15473107 | 0.82 | ELANE (0.62) | ELANECYP2C9 | |
| SCHEMBL15473026 | 0.82 | ELANE (0.62) | ELANECYP2C9 | |
| SCHEMBL15473084 | 0.82 | ELANE (0.61) | ELANECYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010115548-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTITUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | WO | disclosed |