Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873547 | 0.87 | KDM4E (0.32) | ALDH1A1KDM4EHPGD | |
| SCHEMBL7879833 | 0.86 | KDM4E (0.30) | KDM4EHPGD | |
| SCHEMBL7882372 | 0.85 | FFAR1 (0.39) | KDM4EHPGD | |
| SCHEMBL7884377 | 0.83 | CYP1A2 (0.32) | KDM4EHPGD | |
| SCHEMBL7882124 | 0.83 | BRAF (0.35) | KDM4EHPGD | |
| SCHEMBL7873318 | 0.83 | PRSS1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7878276 | 0.83 | CYP1A2 (0.31) | KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7881357 | 0.83 | KDM4E (0.45) | ALDH1A1KDM4EHPGD | |
| SCHEMBL7878061 | 0.83 | NEK2 (0.32) | — | |
| SCHEMBL7880919 | 0.82 | FFAR1 (0.36) | KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248772-B1 | HYPOTENSIVE AGENTS; ANTIARRHYTHMIA AGENTS; ANTIDIABETIC AGENTS; ANTIPROLIFERATIVE AGENTS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6169107-B1 | USEFUL FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY INCREASED SODIUM/PROTON (NA.SUP.+ /H.SUP.+) EXCHANGER ACTIVITY, FOR EXAMPLE, HYPERTENSION, ARRHYTHMIA, ANGINA PECTORIS, CARDIAC HYPERTROPHY, DIABETES MELLITUS | SUMITOMO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-0708091-A2 | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |