SCHEMBL788756

SCHEMBL788756

CCc1[c]cncc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2252234 0.82
SCHEMBL2252883 0.79 CYP2D6 (0.39)
SCHEMBL5544325 0.77 TDP1 (0.42)
SCHEMBL2562076 0.76
SCHEMBL595771 0.76
SCHEMBL2561741 0.76
SCHEMBL17103555 0.76 GSK3B (0.32)
SCHEMBL18230159 0.76
SCHEMBL4929105 0.76
SCHEMBL5747947 0.76 TDP1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2227320-B1 BLOCK COPOLYMER MODIFIED VEGETABLE OIL AND POLYMER BLENDS AND METHODS OF MAKING SAME TOYOTA ENG & MFG NORTH AMERICA (US) 2012-08-29 EP claimed
JP-2011506752-A 2011-03-03 JP claimed
US-7888418-B2 comprises polylactide homopolymer with vegetable oil dispersed inside TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) 2011-02-15 US claimed
EP-2227320-A1 BLOCK COPOLYMER MODIFIED VEGETABLE OIL AND POLYMER BLENDS AND METHODS OF MAKING SAME Toyota Motor Engineering & Manufacturing North America, Inc. (US) 2010-09-15 EP claimed
US-7629342-B2 Regulation of appetite, antiemetics, immunosuppression, analgesia, inflammation, antinocioception, sedation, and intraocular pressure; synergistic; 2-(4-(Trifluoromethyl)benzyl)-7,8-bis(4-chlorophenyl)-6-(methylamino)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one BRISTOL-MYERS SQUIBB COMPANY (US) 2009-12-08 US claimed
EP-1348706-B1 SUBSTITUTED THIAZOLE DERIVATIVES BEARING 3-PYRIDYL GROUPS, PROCESS FOR PREPARING THE SAME AND USE THEREOF TAKEDA PHARMACEUTICAL (JP) 2009-08-19 EP claimed
WO-2009079313-A1 BLOCK COPOLYMER MODIFIED VEGETABLE OIL AND POLYMER BLENDS AND METHODS OF MAKING SAME TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) 2009-06-25 WO claimed
US-20090156746-A1 BLOCK COPOLYMER MODIFIED VEGETABLE OIL AND POLYMER BLENDS AND METHODS OF MAKING SAME TOYOTA MOTOR CORPORATION (JP) 2009-06-18 US claimed
CN-101238128-A Azabicyclic heterocycles as cannabinoid receptor modulators BRISTOL MYERS SQUIBB CO (US) 2008-08-06 CN claimed
US-20060287323-A1 Azabicyclic heterocycles as cannabinoid receptor modulators BRISTOL-MYERS SQUIBB COMPANY 2006-12-21 US claimed
US-20040072876-A1 Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-04-15 US claimed
EP-1348706-A1 SUBSTITUTED THIAZOLE DERIVATIVES BEARING 3-PYRIDYL GROUPS, PROCESS FOR PREPARING THE SAME AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2003-10-01 EP claimed
EP-2735562-B2 Estrogen receptor modulators and uses thereof SERAGON PHARMACEUTICALS INC (US) 2023-11-15 EP disclosed
US-20210386069-A1 PYRIDYLPHENYLAMINOQUINOLINES AND ANALOGUES BAYER AKTIENGESELLSCHAFT (DE) 2021-12-16 US disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed
US-5614624-A THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES SANKYO COMPANY, LIMITED (JP) 1997-03-25 US disclosed
US-5541317-A PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS SANKYO COMPANY, LIMITED (JP) 1996-07-30 US disclosed
CN-1068108-A Be used to prepare the aza cyclo-butanone derivatives of carbapenem antibiotics SANKYO CO (JP) 1993-01-20 CN disclosed
EP-0516486-A2 Azetidinone derivatives useful in the preparation of carbapenem antibiotics Sankyo Company Limited (JP) 1992-12-02 EP disclosed