Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | VDR | P11473 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888395 | 1.00 | CDC25A (0.51) | CDC25ACDC25BVDRHDAC3HDAC6 | |
| SCHEMBL7888393 | 1.00 | CDC25A (0.51) | CDC25ACDC25BVDRHDAC3HDAC6 | |
| SCHEMBL7776433 | 0.90 | CDC25A (0.48) | CDC25ACDC25BVDRGPBAR1MEN1 | |
| SCHEMBL7776424 | 0.90 | CDC25A (0.48) | CDC25ACDC25BVDRGPBAR1MEN1 | |
| SCHEMBL7776428 | 0.90 | CDC25A (0.48) | CDC25ACDC25BVDRGPBAR1MEN1 | |
| SCHEMBL16882254 | 0.89 | CDC25A (0.49) | CDC25ACDC25BVDRGPBAR1MEN1 | |
| SCHEMBL7888317 | 0.81 | CDC25A (0.55) | CDC25ACDC25BVDRHDAC3HDAC6 | |
| SCHEMBL7888321 | 0.81 | CDC25A (0.55) | CDC25ACDC25BVDRHDAC3HDAC6 | |
| SCHEMBL7888323 | 0.81 | CDC25A (0.55) | CDC25ACDC25BVDRHDAC3HDAC6 | |
| SCHEMBL16152770 | 0.81 | CDC25A (0.43) | CDC25ACDC25BVDRGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177586-B1 | USEFUL AS A PHARMACEUTICAL SUCH AS AN AGENT FOR PROMOTING BONE FORMATION, AN AGENT FOR SUPPRESSING PROLIFERATION OF TUMOR CELLS, AN AGENT FOR HIGH CALCIUM BLOOD DISEASES, AND AN IMMUNOSUPPRESSION AGENT | TEIJIN LIMITED (JP) | 2001-01-23 | — | — | US | disclosed |
| EP-0712843-B1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| US-5986112-A | STEROID DERIVATIVES AS ANTITUMOR AGENTS AND BLOOD METAL CONCENTRATES | TEIJIN LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5719297-A | Vitamin D3 derivatives and production process thereof | TEIJIN LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0712843-A1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |