Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116611 | 1.00 | ELANE (0.84) | ELANECYP3A4CYP2C9 | |
| SCHEMBL587332 | 1.00 | ELANE (0.84) | ELANECYP3A4CYP2C9 | |
| SCHEMBL18839888 | 0.93 | ELANE (0.83) | ELANECYP3A4CYP2C9 | |
| SCHEMBL123593 | 0.93 | ELANE (0.83) | ELANECYP3A4CYP2C9 | |
| SCHEMBL2117084 | 0.91 | ELANE (1.00) | ELANECYP3A4CYP2C9 | |
| SCHEMBL15866526 | 0.91 | ELANE (1.00) | ELANECYP3A4CYP2C9 | |
| SCHEMBL586622 | 0.91 | ELANE (1.00) | ELANECYP3A4CYP2C9 | |
| SCHEMBL3717555 | 0.90 | ELANE (0.74) | ELANECYP3A4CYP2C9 | |
| SCHEMBL121093 | 0.90 | ELANE (0.74) | ELANECYP3A4CYP2C9 | |
| SCHEMBL3801998 | 0.90 | ELANE (0.70) | ELANECYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010115548-A1 | SULFONIC AMIDE AND SULFOXIMINE-SUBSTITUTED DIARYL-DIHYDROPYRIMIDINONES AND USAGE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | WO | disclosed |