Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.62 |
| ▸ | F10 | P00742 | 18/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 18/20 | 0.62 |
| ▸ | F2 | P00734 | 16/20 | 0.62 |
| ▸ | F3 | P13726 | 14/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5882939 | 0.79 | F7 (0.58) | F7F10PRSS1F2F3 | |
| SCHEMBL5882165 | 0.79 | F7 (0.58) | F7F10PRSS1F2F3 | |
| Hydrochloric Acid SCHEMBL5882421 | 0.78 | F7 (0.77) | F7F10PRSS1F2F3 | |
| Hydrochloric Acid SCHEMBL5883182 | 0.78 | F7 (0.57) | F7F10PRSS1F2F3 | |
| Hydrochloric Acid SCHEMBL5882629 | 0.78 | F7 (0.57) | F7F10PRSS1F2F3 | |
| Hydrochloric Acid SCHEMBL5883646 | 0.78 | F7 (0.57) | F7F10PRSS1F2F3 | |
| Hydrochloric Acid SCHEMBL5882561 | 0.78 | F7 (0.57) | F7F10PRSS1F2F3 | |
| SCHEMBL5882039 | 0.78 | F7 (0.61) | F7F10PRSS1F2F3 | |
| SCHEMBL5881806 | 0.78 | F7 (0.85) | F7F10PRSS1F2F3 | |
| SCHEMBL5882942 | 0.78 | F7 (0.85) | F7F10PRSS1F2F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242644-B1 | FOR TREATING THROMBOSIS, APOPLEXY, CARDIAC INFARCTION, INFLAMATION AND ARTHEROSCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-06-05 | — | — | US | disclosed |