Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 19/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900796 | 0.89 | SLC6A4 (0.74) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7899271 | 0.87 | SLC6A4 (0.72) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7898883 | 0.85 | SLC6A4 (0.68) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5307133 | 0.83 | SLC6A4 (0.66) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL17708138 | 0.77 | SLC6A4 (0.62) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL17452663 | 0.76 | SLC6A4 (0.56) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7901520 | 0.75 | SLC6A4 (0.59) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3466798 | 0.74 | SLC6A4 (0.67) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3466794 | 0.74 | SLC6A4 (0.67) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3521193 | 0.74 | SLC6A4 (1.00) | SLC6A3SLC6A4SLC6A2GAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091268-A1 | PYRROLIDINE TRIPLE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2010-08-12 | — | — | WO | disclosed |