Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2C | Q14957 | 12/20 | 0.80 |
| ▸ | TP53 | P04637 | 3/20 | 0.80 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901342 | 0.94 | GRIN2C (0.90) | GRIN2CTP53GRIN2DGAAHTT | |
| SCHEMBL7895810 | 0.90 | GRIN2C (0.83) | GRIN2CTP53GRIN2D | |
| SCHEMBL7900445 | 0.89 | GRIN2C (0.82) | GRIN2CTP53GRIN2DGAAHTT | |
| SCHEMBL7893874 | 0.89 | GRIN2C (1.00) | GRIN2CTP53GRIN2D | |
| SCHEMBL7901977 | 0.89 | GRIN2C (1.00) | GRIN2CTP53GRIN2D | |
| SCHEMBL7899442 | 0.87 | TP53 (0.82) | GRIN2CTP53GRIN2DGAAHTT | |
| SCHEMBL7894045 | 0.87 | GRIN2C (0.81) | GRIN2CTP53GRIN2DGAAHTT | |
| SCHEMBL20953059 | 0.86 | GRIN2C (0.76) | GRIN2CTP53GRIN2D | |
| SCHEMBL7902664 | 0.85 | GRIN2C (0.82) | GRIN2CTP53GRIN2D | |
| SCHEMBL7894774 | 0.85 | GRIN2C (1.00) | GRIN2CTP53GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088414-A2 | SUBUNIT SELECTIVE NMDA RECEPTOR POTENTIATORS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | EMORY UNIVERSITY (US) | 2010-08-05 | — | — | WO | disclosed |