Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894932 | 0.89 | CHRM1 (0.55) | CHRM1CHRM2 | |
| SCHEMBL7818708 | 0.88 | CHRM1 (0.57) | CHRM1CHRM2 | |
| SCHEMBL7818950 | 0.85 | CHRM1 (0.57) | CHRM1CHRM2 | |
| SCHEMBL7809546 | 0.85 | CHRM1 (0.71) | CHRM1CHRM2 | |
| SCHEMBL6784896 | 0.84 | CHRM1 (0.53) | CHRM1CHRM2 | |
| SCHEMBL6784734 | 0.81 | CHRM1 (0.54) | CHRM1CHRM2 | |
| SCHEMBL6780813 | 0.81 | CHRM1 (0.56) | CHRM1CHRM2 | |
| SCHEMBL7819289 | 0.80 | CHRM1 (0.58) | CHRM1CHRM2 | |
| SCHEMBL7894513 | 0.80 | CHRM1 (0.51) | CHRM1CHRM2 | |
| SCHEMBL7821961 | 0.79 | CHRM1 (0.55) | CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187798-B1 | (+-)EXO-3-(3-(4-CHLOROPHENYL)PROPYNYLOXY-4-(1 -AZABICYCLO(2.2.1)HEPTYL-3-OXY)-1,2,5-THIADIAZOLE, FOR EXAMPLE; FOR MODULATING A MUSCARINIC RECEPTOR; TREATING ALZHEIMER'S DISEASE OR PSYCHOSIS | ELI LILLY AND COMPANY | 2001-02-13 | — | — | US | disclosed |