Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498332 | 0.93 | EGFR (0.49) | EGFRLMNAKDM4ENPC1POLB | |
| SCHEMBL8695046 | 0.83 | NPSR1 (0.63) | LMNAKDM4ENPC1GLAPOLB | |
| Hydrochloric Acid SCHEMBL8692152 | 0.81 | NPSR1 (0.62) | LMNAKDM4ENPC1GLAPOLB | |
| SCHEMBL5491242 | 0.81 | EGFR (0.58) | EGFRFLT3LMNAKDM4ENPC1 | |
| SCHEMBL1255024 | 0.79 | TSHR (0.57) | EGFRLMNAKDM4ENPC1GLA | |
| SCHEMBL16620777 | 0.77 | KDM4E (0.51) | FLT3KDM4EKMT2AALDH1A1RXFP1 | |
| SCHEMBL3114904 | 0.76 | POLB (0.54) | EGFRLMNAKDM4ENPC1GLA | |
| SCHEMBL16621319 | 0.76 | MAPK1 (0.46) | LMNAKMT2AALDH1A1TSHRSIGMAR1 | |
| SCHEMBL5488941 | 0.74 | EGFR (0.56) | EGFRLMNAPOLBKMT2ARXFP1 | |
| SCHEMBL16621192 | 0.73 | MAPT (0.54) | KDM4EPOLBKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |