SCHEMBL7896028 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	HDAC3	O15379	16/20	0.51

▸	HDAC1	Q13547	16/20	0.51

▸	HDAC8	Q9BY41	14/20	0.51

▸	HDAC6	Q9UBN7	8/20	0.51

▸	HDAC4	P56524	7/20	0.51

▸	HDAC5	Q9UQL6	6/20	0.51

▸	HDAC2	Q92769	13/20	0.46

▸	HDAC10	Q969S8	3/20	0.44

▸	MEF2D	Q14814	2/20	0.43

▸	KDM1A	O60341	2/20	0.41

▸	MAOA	P21397	1/20	0.41

▸	HDAC7	Q8WUI4	2/20	0.40

▸	HDAC11	Q96DB2	2/20	0.40

▸	HDAC9	Q9UKV0	2/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL181804	0.89	HDAC3 (0.55)	HDAC3HDAC1HDAC8HDAC6HDAC4
SCHEMBL7897375	0.89	HDAC3 (0.55)	HDAC3HDAC1HDAC8HDAC6HDAC4
SCHEMBL7898196	0.89	HDAC3 (0.54)	HDAC3HDAC1HDAC8HDAC6HDAC4
SCHEMBL9895471	0.89	HDAC3 (0.54)	HDAC3HDAC1HDAC8HDAC6HDAC4
SCHEMBL7896020	0.89	HDAC3 (0.54)	HDAC3HDAC1HDAC8HDAC6HDAC4
SCHEMBL9895152	0.89	HDAC3 (0.54)	HDAC3HDAC1HDAC8HDAC6HDAC4
SCHEMBL7897997	0.88	HDAC3 (0.56)	HDAC3HDAC1HDAC8HDAC6HDAC4
SCHEMBL9895603	0.88	HDAC3 (0.56)	HDAC3HDAC1HDAC8HDAC6HDAC4
SCHEMBL2704438	0.85	HDAC3 (0.50)	HDAC3HDAC1HDAC8HDAC6HDAC4
SCHEMBL2704435	0.85	HDAC3 (0.50)	HDAC3HDAC1HDAC8HDAC6HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010097586-A1	ENZYME INHIBITORS	CHROMA THERAPEUTICS LTD. (GB)	2010-09-02	—	—	WO	disclosed