Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896831 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL6556802 | 0.88 | MAPT (0.52) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL6556797 | 0.88 | MAPT (0.52) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL6556803 | 0.88 | MAPT (0.52) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL6556876 | 0.86 | KMT2A (0.47) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL6556888 | 0.86 | KMT2A (0.47) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL6556885 | 0.86 | KMT2A (0.47) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL6554806 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL6554796 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL6554811 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194611-B1 | FOR CONTROLLING OR PREVENTION OF PLANT INFESTATION BY PHYTOPATHOGENIC MICROORGANISMS, SUCH AS FUNGI | NOVARTIS CROP PROTECTION, INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0858448-B1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID DERIVATIVES AS MICROBICIDES | NOVARTIS AG (CH) | 2000-05-31 | — | — | EP | disclosed |