SCHEMBL7897332

SCHEMBL7897332

COC(=O)C(O)Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.74
PPARA Q07869 11/20 0.69
PPARD Q03181 4/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7906937 0.92 PPARG (0.71) PPARGPPARAPPARD
SCHEMBL7904793 0.91 PPARG (0.75) PPARGPPARAPPARD
SCHEMBL7904779 0.90 PPARG (0.77) PPARGPPARAPPARD
SCHEMBL7914389 0.89 PPARG (0.73) PPARGPPARAPPARD
SCHEMBL3049053 0.89 PPARG (0.73) PPARGPPARAPPARD
SCHEMBL7157011 0.89 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL7905708 0.89 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL7903537 0.88 PPARG (0.71) PPARGPPARAPPARD
SCHEMBL6385736 0.88 PPARG (0.71) PPARGPPARAPPARD
SCHEMBL6385296 0.88 PPARG (0.71) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204277-B1 TREATING DIABETES JAPAN TOBACCO INC. (JP) 2001-03-20 US disclosed
EP-0930299-A1 PROPIONIC ACID DERIVATIVES AND APPLICATIONS THEREOF Japan Tobacco Inc. (JP) 1999-07-21 EP disclosed