SCHEMBL7897441

SCHEMBL7897441

Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(C(=O)O)C(=O)O)cc1

nearest known ligand 0.81

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.81
PPARA Q07869 14/20 0.80
PPARD Q03181 3/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7906723 0.95 PPARG (0.76) PPARGPPARAPPARD
SCHEMBL7903504 0.94 PPARG (0.74) PPARGPPARAPPARD
SCHEMBL7909886 0.94 PPARG (0.77) PPARGPPARAPPARD
SCHEMBL7904779 0.93 PPARG (0.77) PPARGPPARAPPARD
SCHEMBL7903197 0.93 PPARG (0.77) PPARGPPARAPPARD
SCHEMBL7903200 0.92 PPARG (0.80) PPARGPPARAPPARD
SCHEMBL7904742 0.92 PPARG (0.74) PPARGPPARAPPARD
SCHEMBL7903353 0.92 PPARG (0.79) PPARGPPARAPPARD
SCHEMBL7904793 0.92 PPARG (0.75) PPARGPPARAPPARD
SCHEMBL7897394 0.92 PPARG (0.75) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204277-B1 TREATING DIABETES JAPAN TOBACCO INC. (JP) 2001-03-20 US claimed
EP-0930299-A1 PROPIONIC ACID DERIVATIVES AND APPLICATIONS THEREOF Japan Tobacco Inc. (JP) 1999-07-21 EP claimed
US-20230210808-A1 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS CYMABAY THERAPEUTICS, INC. 2023-07-06 US disclosed
US-6204277-B1 TREATING DIABETES JAPAN TOBACCO INC. (JP) 2001-03-20 US disclosed
EP-0930299-A1 PROPIONIC ACID DERIVATIVES AND APPLICATIONS THEREOF Japan Tobacco Inc. (JP) 1999-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210808-A1 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS PPARA, PPARG, PPARD PPARG 2/4885PPARA 1/4885PPARD 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.