Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17190969 | 0.81 | PARP1 (0.41) | KDM4EMAPT | |
| SCHEMBL27873730 | 0.79 | SRD5A1 (0.39) | KDM4EMAPT | |
| SCHEMBL27873727 | 0.79 | PARP10 (0.40) | KDM4EMAPT | |
| SCHEMBL1857350 | 0.79 | PARP10 (0.40) | KDM4EMAPT | |
| SCHEMBL168071 | 0.79 | PARP10 (0.40) | KDM4EMAPT | |
| SCHEMBL7897372 | 0.79 | SRD5A1 (0.39) | KDM4EMAPT | |
| SCHEMBL159742 | 0.79 | SRD5A1 (0.39) | KDM4EMAPT | |
| SCHEMBL27873729 | 0.77 | MAPT (0.35) | KDM4EMAPT | |
| SCHEMBL7897374 | 0.77 | MAPT (0.35) | KDM4EMAPT | |
| SCHEMBL158376 | 0.77 | MAPT (0.35) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126914-A1 | PYRIDINONE ANTAGONISTS OF ALPHA-4 INTEGRINS | ELAN PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | WO | disclosed |