SCHEMBL7897635

SCHEMBL7897635

CCCCOCCOCCOC(O)CCCC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
HTT P42858 2/20 0.42
MEN1 O00255 1/20 0.42
THRB P10828 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.42
CYP3A4 P08684 3/20 0.41
USP2 O75604 1/20 0.37
TDP1 Q9NUW8 1/20 0.34
PLA2G2C Q5R387 1/20 0.34
SPHK1 Q9NYA1 1/20 0.33
RARB P10826 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
LPAR5 Q9H1C0 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
CES2 O00748 1/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1026986 1.00 TSHR (0.46) TSHRHTTMEN1THRBKMT2A
SCHEMBL14119419 0.87 TSHR (0.37) TSHRCYP3A4USP2TDP1CYP2C19
SCHEMBL13435130 0.86 TSHR (0.42) TSHRHTTMEN1THRBKMT2A
SCHEMBL5477288 0.85 TSHR (0.48) TSHRHTTMEN1THRBKMT2A
SCHEMBL5598774 0.83 TSHR (0.46) TSHRHTTMEN1THRBKMT2A
SCHEMBL28108582 0.83 TSHR (0.46) TSHRHTTMEN1THRBKMT2A
SCHEMBL27830951 0.83 TSHR (0.52) TSHRHTTMEN1THRBKMT2A
SCHEMBL28334551 0.83 TSHR (0.52) TSHRHTTMEN1THRBKMT2A
SCHEMBL20590292 0.83 TSHR (0.46) TSHRHTTMEN1THRBKMT2A
SCHEMBL27483722 0.82 MEN1 (0.57) TSHRHTTMEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6177394-B1 NONIONIC SURFACTANT CONTAINING ETHOXYLATE GROUPS, A LIQUID CRYSTAL SUPPRESSION ADDITIVE SELECTED FROM 1,2-ALKANEDIOLS OF 5-8 CARBON ATOMS, A C7-17 N-ALKYL PYRROLIDONE, AN ALKYL UREA AND AN ESTERIFIED (POLY)ETHYLENE OXIDE OF GIVEN FORMULA COLGATE-PALMOLIVE CO 2001-01-23 US disclosed