Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | AHR | P35869 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732658 | 0.95 | MAPK1 (0.57) | MAPK1AHRNPC1GAAHSP90AA1 | |
| SCHEMBL9732232 | 0.91 | AHR (0.57) | MAPK1AHRNPC1GAAHSP90AA1 | |
| SCHEMBL3757554 | 0.90 | NPC1 (0.65) | MAPK1NPC1GAAHSP90AA1HSP90AB1 | |
| Chloroneb SCHEMBL22739 | 0.84 | GAA (0.64) | MAPK1NPC1GAAHSP90AA1TAAR1 | |
| SCHEMBL16609990 | 0.82 | GAA (0.68) | MAPK1NPC1GAAHSP90AA1HSP90AB1 | |
| SCHEMBL10356771 | 0.80 | GAA (0.54) | MAPK1NPC1GAAHSP90AA1HSP90AB1 | |
| SCHEMBL30487990 | 0.79 | GAA (0.65) | MAPK1NPC1GAAHSP90AA1TAAR1 | |
| SCHEMBL27952777 | 0.79 | GAA (0.65) | MAPK1NPC1GAAHSP90AA1TAAR1 | |
| SCHEMBL5572861 | 0.79 | GAA (0.50) | MAPK1NPC1GAAHSP90AA1TAAR1 | |
| SCHEMBL7897905 | 0.77 | HSP90AA1 (0.46) | MAPK1AHRNPC1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204005-B1 | ACCURATE AND SENSITIVE QUALITATIVE OR QUANTITATIVE ANALYSIS BY INCUBATING ANTIBODIES AND COMPETITOR OF DEFINED STRUCTURE IN PRESENCE OF TEST SAMPLE, THEN DETECTING CONGENER | ECOCHEM RESEARCH, INC. | 2001-03-20 | — | — | US | disclosed |
| US-5538852-A | QUALITATIVE OR QUANTITATIVE ANALYSIS WITH COMPETITORS AND ANTIBODIES | ECOCHEM RESEARCH, INC. (US) | 1996-07-23 | — | — | US | disclosed |
| US-5145790-A | Immunoassay, fluorescein derivative | ABBOTT LABORATORIES (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0455058-A2 | Reagents and method for detecting polychlorinated biphenyls | ABBOTT LABORATORIES (US) | 1991-11-06 | — | — | EP | disclosed |