SCHEMBL7897889

SCHEMBL7897889

COC(=O)CCCCc1cc(Cl)ccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.49
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.43
EGFR P00533 1/20 0.42
KAT2B Q92831 1/20 0.42
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14609800 0.89 MAPT (0.54) MAPTL3MBTL1CYP1A2CYP3A4CYP2C19
SCHEMBL7905467 0.81 F13A1 (0.53) MAPT
SCHEMBL13002998 0.81 MAPT (0.52) MAPTL3MBTL1CYP1A2CYP3A4CYP2C19
SCHEMBL15060231 0.80 CYP4F2 (0.46) MAPTL3MBTL1HPGDKAT2BTSHR
SCHEMBL20672330 0.80 F13A1 (0.56) MAPT
SCHEMBL7133160 0.79 MAPT (0.49) MAPTL3MBTL1CYP1A2CYP3A4CYP2C19
SCHEMBL15053273 0.79 MAPT (0.43) MAPTL3MBTL1CYP1A2CYP3A4CYP2C19
SCHEMBL8094260 0.78 MAPT (0.57) MAPTL3MBTL1CYP1A2CYP3A4CYP2C19
SCHEMBL15876199 0.78 MAPT (0.46) MAPTL3MBTL1CYP1A2CYP3A4CYP2C19
SCHEMBL20672378 0.78 NPC1 (0.45) HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204005-B1 ACCURATE AND SENSITIVE QUALITATIVE OR QUANTITATIVE ANALYSIS BY INCUBATING ANTIBODIES AND COMPETITOR OF DEFINED STRUCTURE IN PRESENCE OF TEST SAMPLE, THEN DETECTING CONGENER ECOCHEM RESEARCH, INC. 2001-03-20 US disclosed
US-5674697-A High sensitivity immunoassay for polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans ECOCHEM RESEARCH, INC. (US) 1997-10-07 US disclosed
US-5538852-A QUALITATIVE OR QUANTITATIVE ANALYSIS WITH COMPETITORS AND ANTIBODIES ECOCHEM RESEARCH, INC. (US) 1996-07-23 US disclosed