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Lithium Ion

Lithium Ion

SCHEMBL7897899

CSCC[C@H](NC(=O)c1ccc(COC2CCC(NC(=O)OC(C)(C)C)CC2)cc1-c1ccccc1C)C(=O)[O-].[Li+]

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 10/20 0.57
▸ FNTB P49356 10/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588577 0.93 FNTA (0.57) FNTAFNTB
SCHEMBL8588580 0.93 FNTA (0.57) FNTAFNTB
SCHEMBL7897898 0.92 FNTA (0.57) FNTAFNTB
SCHEMBL7897903 0.92 FNTA (0.57) FNTAFNTB
Lithium Ion SCHEMBL7905945 0.87 FNTA (0.57) FNTAFNTB
Lithium Ion SCHEMBL7910460 0.82 FNTA (0.61) FNTAFNTB
SCHEMBL8590258 0.80 FNTA (0.57) FNTAFNTB
SCHEMBL7905950 0.79 FNTA (0.57) FNTAFNTB
SCHEMBL7905943 0.79 FNTA (0.57) FNTAFNTB
Lithium Ion SCHEMBL7907142 0.79 FNTA (0.79) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 — — US disclosed