Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | HTR1A | P08908 | 1/20 | 0.71 |
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | HRH1 | P35367 | 1/20 | 0.71 |
| ▸ | HTR2B | P41595 | 1/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.71 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898738 | 1.00 | TACR1 (0.79) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL6556178 | 1.00 | TACR1 (0.79) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8539292 | 0.99 | TACR1 (0.77) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL9294358 | 0.97 | TACR1 (0.74) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL9294289 | 0.94 | TACR1 (0.69) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL9294296 | 0.94 | TACR1 (0.69) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL9294292 | 0.94 | TACR1 (0.69) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL6554923 | 0.92 | TACR1 (0.79) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8540841 | 0.91 | TACR1 (0.78) | TACR1CYP2D6KCNH2HTR1AHTR2A | |
| SCHEMBL6557108 | 0.91 | TACR1 (0.77) | TACR1CYP2D6KCNH2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194436-B1 | THERAPY FOR LUNG CANCER | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |