Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907832 | 0.91 | PDE4A (0.78) | PDE4A | |
| SCHEMBL7911671 | 0.87 | PDE4A (0.90) | PDE4A | |
| SCHEMBL7899107 | 0.86 | PDE4A (0.61) | PDE4A | |
| SCHEMBL7905253 | 0.85 | PDE4A (0.78) | PDE4A | |
| SCHEMBL7908344 | 0.85 | PDE4A (0.57) | PDE4A | |
| SCHEMBL7906802 | 0.84 | PDE4A (0.66) | PDE4A | |
| SCHEMBL7899087 | 0.83 | PDE4A (0.79) | PDE4A | |
| SCHEMBL7899113 | 0.83 | PDE4A (0.79) | PDE4A | |
| SCHEMBL7906644 | 0.82 | PDE4A (1.00) | PDE4A | |
| SCHEMBL7905283 | 0.82 | PDE4A (0.79) | PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200993-B1 | ASTHMA; ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-03-13 | — | — | US | claimed |
| US-6200993-B1 | ASTHMA; ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-03-13 | — | — | US | disclosed |