⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146146 | 1.00 | — | — | |
| SCHEMBL8184207 | 1.00 | KDM1A (0.34) | — | |
| SCHEMBL4579974 | 1.00 | KDM1A (0.34) | — | |
| SCHEMBL23532635 | 1.00 | KDM1A (0.34) | — | |
| SCHEMBL4577624 | 1.00 | KDM1A (0.34) | — | |
| SCHEMBL23532670 | 1.00 | — | — | |
| SCHEMBL3958 | 0.97 | — | — | |
| SCHEMBL2808 | 0.88 | — | — | |
| Ethylene SCHEMBL28695708 | 0.71 | TYMP (0.38) | — | |
| SCHEMBL3233355 | 0.69 | TYMP (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105482-A1 | Urea Glucokinase Activators | NOVO NORDISK A/S (DK) | 2009-04-23 | — | — | US | claimed |
| JP-2009501198-A | — | — | 2009-01-15 | — | — | JP | claimed |
| CN-101263131-A | Urea glucokinase activators | NOVO NORDISK AS (US) | 2008-09-10 | — | — | CN | claimed |
| EP-1904467-A1 | UREA GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | claimed |
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | claimed |
| US-6348471-B1 | FUNGICIDES, AND ALSO TO NOVEL INTERMEDIATES AND TO A PROCESS FOR THEIR PREPARATION. | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-19 | — | — | US | claimed |
| EP-1000037-A1 | PYRIMIDYL OXYPHENYLACETIC ACID DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2000-05-17 | — | — | EP | claimed |
| WO-1999005122-A1 | PYRIMIDYL OXYPHENYLACETIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | claimed |
| EP-0103798-B1 | SUBSTITUTED AZOLYLALKYL-T.BUTYL KETONES AND CARBINOLS | BAYER AG (DE) | 1986-12-30 | — | — | EP | claimed |
| EP-0103798-A2 | Substituted azolylalkyl-t.butyl ketones and carbinols | BAYER AG (DE) | 1984-03-28 | — | — | EP | claimed |
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | BASF SE (DE) | 2019-02-19 | — | — | US | disclosed |
| EP-2277510-B1 | Controlled release preparation | TAKEDA PHARMACEUTICALS CO (JP) | 2018-12-26 | — | — | EP | disclosed |
| EP-2275088-B2 | Method for producing granules | TAKEDA PHARMACEUTICALS CO (JP) | 2018-09-26 | — | — | EP | disclosed |
| CN-105073735-B | Halogen-substituted pyrazole derivatives as pest control agents | 拜耳作物科学股份公司 | 2018-08-14 | — | — | CN | disclosed |
| EP-2970321-B1 | BUPRENORPHINE ANALOGS | PURDUE PHARMA LP (US) | 2018-06-27 | — | — | EP | disclosed |
| EP-0000485-A1 | Piperidino-propanols, their preparation and pharmaceutical compounds containing them | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |
| US-4120978-A | Pharmaceutical composition for inhibiting and blocking cardioselective beta-receptors | CIBA-GEIGY CORPORATION (US) | 1978-10-17 | — | — | US | disclosed |
| US-4038313-A | INHIBITORS OF CARDIAC BETA-RECEPTORS | CIBA-GEIGY CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
| US-3968142-A | ANALGESIC, ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |
| US-3935259-A | 2-HYDROXY-3-(UREIDOPHENOXY)PROPYL, CARDIAC BETA RECEPTOR INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |