Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.59 |
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | HRH2 | P25021 | 3/20 | 0.52 |
| ▸ | HRH1 | P35367 | 3/20 | 0.52 |
| ▸ | DRD1 | P21728 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897827 | 0.90 | HRH4 (0.56) | HRH4DRD2OPRD1DRD4CYP2D6 | |
| SCHEMBL7895657 | 0.89 | HRH4 (0.59) | HRH4DRD2OPRD1DRD4CYP2D6 | |
| SCHEMBL7905704 | 0.88 | HRH4 (0.53) | HRH4DRD2OPRD1DRD4CYP2D6 | |
| SCHEMBL7903151 | 0.88 | HRH4 (0.56) | HRH4DRD2OPRD1DRD4CYP2D6 | |
| SCHEMBL7899467 | 0.86 | HRH4 (0.59) | HRH4DRD2OPRD1DRD4CYP2D6 | |
| SCHEMBL7904539 | 0.86 | HRH4 (0.59) | HRH4DRD2OPRD1DRD4CYP2D6 | |
| SCHEMBL7904003 | 0.84 | HRH4 (0.56) | HRH4DRD2OPRD1DRD4CYP2D6 | |
| SCHEMBL7907196 | 0.83 | HRH4 (0.57) | HRH4DRD2OPRD1DRD4CYP2D6 | |
| SCHEMBL7903719 | 0.80 | HRH4 (0.58) | HRH4DRD2OPRD1DRD4CYP2D6 | |
| SCHEMBL1367220 | 0.78 | HRH4 (0.64) | HRH4DRD2OPRD1DRD4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062565-A1 | MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS INC. (US) | 2010-06-03 | — | — | WO | disclosed |