Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12044506 | 0.92 | GRIN2D (0.42) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7907327 | 0.86 | GRIN2D (0.42) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL1723437 | 0.78 | SMN1; SMN2 (0.53) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7898104 | 0.77 | GRIN2D (0.44) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7899483 | 0.76 | GRIN2D (0.44) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7909018 | 0.75 | GRIN2D (0.51) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7906746 | 0.74 | GRIN2D (0.53) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7905781 | 0.73 | GRIN2D (0.46) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7899490 | 0.72 | MAPK1 (0.52) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL7899480 | 0.72 | GRIN2D (0.50) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101230-A1 | QUINOXALINE COMPOUNDS | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |