⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7977630 | 0.88 | — | — | |
| Bromide SCHEMBL17434706 | 0.88 | — | — | |
| Piperazine SCHEMBL3888557 | 0.83 | HIF1A (0.33) | — | |
| SCHEMBL2360350 | 0.79 | — | — | |
| SCHEMBL8976021 | 0.79 | — | — | |
| Pyrrole SCHEMBL1456290 | 0.77 | — | — | |
| SCHEMBL1036248 | 0.74 | — | — | |
| SCHEMBL125300 | 0.74 | — | — | |
| SCHEMBL1835539 | 0.72 | — | — | |
| SCHEMBL1835541 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194577-B1 | OXIDIZING 1-AMINOPYRROLIDINE IN PRESENCE OF INORGANIC BASE WITH AIR, OXYGEN OR AQUEOUS HYDROGEN PEROXIDE AS AN OXIDIZING AGENT TO FORM TETRAHYDROPYRIDAZINE | JAPAN HYDRAZINE CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| US-5977360-A | Process for producing cyclic hydrazine derivatives, tetra-hydropyridazine and hexahydropyridazine | JAPAN HYDRAZINE CO., LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0850930-A2 | A process for producing alicyclic hydrazine derivatives, tetra-hydropyridazine and hexahydropyridazine | JAPAN HYDRAZINE CO., LTD. (JP) | 1998-07-01 | — | — | EP | disclosed |