SCHEMBL7900074

SCHEMBL7900074

CNC(Cc1ccc(-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MME P08473 14/20 0.63
ACE2 Q9BYF1 13/20 0.63
ACE P12821 12/20 0.63
CPA1 P15085 11/20 0.63
MMP2 P08253 4/20 0.56
MMP9 P14780 3/20 0.56
ADAMTS4 O75173 1/20 0.56
SRR Q9GZT4 1/20 0.54
PSAT1 Q9Y617 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29067592 1.00 MME (0.63) MMEACE2ACECPA1MMP2
SCHEMBL12331937 1.00 MME (0.63) MMEACE2ACECPA1MMP2
SCHEMBL7937827 0.91 MME (0.57) MMEMMP2MMP9
SCHEMBL38480 0.91 MME (0.57) MMEMMP2MMP9
SCHEMBL38479 0.91 MME (0.57) MMEMMP2MMP9
SCHEMBL161255 0.91 MME (0.57) MMEMMP2MMP9
SCHEMBL1324555 0.89 MME (0.56) MMEMMP2MMP9
SCHEMBL1324550 0.89 MME (0.56) MMEMMP2MMP9
Hydrochloric Acid SCHEMBL901419 0.89 MME (0.56) MMEMMP2MMP9
Hydrochloric Acid SCHEMBL7323325 0.89 MME (0.56) MMEMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116710469-A Linear Apelin receptor agonists 赫帕雷斯治疗有限公司 2023-09-05 CN claimed
CN-116710469-A Linear Apelin receptor agonists 赫帕雷斯治疗有限公司 2023-09-05 CN disclosed
EP-2890672-B1 PROCESSES FOR PREPARING INTERMEDIATES FOR THE MANUFACTURE OF NEP INHIBITORS NOVARTIS AG (CH) 2018-05-30 EP disclosed
US-20170097567-A1 METHOD FOR PRODUCING POLYMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-06 US disclosed
US-20160229940-A1 POLYMER, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-11 US disclosed
WO-2010081410-A1 PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) 2010-07-22 WO disclosed
WO-2007008603-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS, INC. (US) 2007-01-18 WO disclosed