Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784680 | 1.00 | CYP3A4 (0.54) | CYP3A4LPAR3LPAR2LPAR1FAAH | |
| SCHEMBL7738766 | 0.98 | CYP3A4 (0.56) | CYP3A4LPAR3LPAR2LPAR1FAAH | |
| SCHEMBL11165391 | 0.96 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1FAAH | |
| SCHEMBL27636765 | 0.96 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1FAAH | |
| SCHEMBL27826280 | 0.96 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1FAAH | |
| SCHEMBL27636762 | 0.96 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1FAAH | |
| SCHEMBL7269332 | 0.96 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1FAAH | |
| SCHEMBL9309241 | 0.93 | LPAR3 (0.54) | CYP3A4LPAR3LPAR2LPAR1FAAH | |
| SCHEMBL575395 | 0.91 | CYP3A4 (0.58) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL27480355 | 0.87 | LPAR3 (0.57) | CYP3A4LPAR3LPAR2LPAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194605-B1 | REACTING DIALKYLPHOSPHINIC ACID ESTER OR DIPHOSPHINIC ACID ESTER IN PRESENCE OF SOLVENT AND REACTION SATURATED ALIPHATIC MONOCARBOXYLIC ACID WITH ALUMINUM HYDROXIDE IN A CLOSED PRESSURE-RESISTANT REACTION VESSEL | TICONA GMBH (DE) | 2001-02-27 | — | — | US | disclosed |