SCHEMBL7900545

SCHEMBL7900545

CCC[C@H]1CC[C@H](C(=O)Oc2ccc(OC)cc2)CC1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.51
KMT2A Q03164 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
F2 P00734 1/20 0.47
ELANE P08246 2/20 0.47
MAPT P10636 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 1/20 0.43
ATM Q13315 1/20 0.41
POLB P06746 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7900546 1.00 HTT (0.51) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL11412070 0.96 KMT2A (0.47) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL13135346 0.94 HTT (0.58) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL7913960 0.92 HTT (0.49) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL7913964 0.92 HTT (0.49) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL1896520 0.90 HTT (0.47) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL7762458 0.90 HTT (0.47) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL7887235 0.88 KMT2A (0.51) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL12012965 0.88 KMT2A (0.51) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL7887233 0.88 KMT2A (0.51) HTTKMT2ASMN1; SMN2TDP1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112210156-A Ceramic halogen-free flame-retardant polymer composite material and application thereof 宁夏师范学院 2021-01-12 CN claimed
CN-112210156-B Ceramic halogen-free flame-retardant polymer composite material and application thereof 宁夏师范学院 2023-03-17 CN disclosed
CN-112210156-A Ceramic halogen-free flame-retardant polymer composite material and application thereof 宁夏师范学院 2021-01-12 CN disclosed
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
US-5318721-A Nematic liquid-crystalline phases MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-06-07 US disclosed
US-5286410-A Positive dielectric anisotropy MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-02-15 US disclosed
US-5271865-A Liquid-crystalline mixture of low viscosity MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-12-21 US disclosed
US-5248447-A 2,3-difluorohydroquinone derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-09-28 US disclosed
US-4935160-A Liquid-crystal guest-host systems MERCK PATENT GESSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-06-19 US disclosed
US-4882082-A PYRIMIDINE DERIVATIVE LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-11-21 US disclosed
US-4871469-A TRIFLUOROTOLUENE DERIVATIVES BESCRANKTER HAFTUNG (DE) 1989-10-03 US disclosed
EP-0332005-A1 Supertwist liquid-crystal display MERCK PATENT GmbH (DE) 1989-09-13 EP disclosed
US-4752414-A LIQUID CRYSTAL PHASES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-06-21 US disclosed
US-4737312-A Liquid crystal composition MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-04-12 US disclosed
US-4713197-A Nitrogen-containing heterocyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-12-15 US disclosed
US-4704227-A DERIVATIVES OF 1,3-DIOXANE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-11-03 US disclosed
US-4659502-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-04-21 US disclosed
US-4639328-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-01-27 US disclosed