Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900597 | 1.00 | MEN1 (0.55) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL10832031 | 1.00 | MEN1 (0.55) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL1658450 | 0.98 | MEN1 (0.56) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL261024 | 0.98 | MEN1 (0.56) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7902526 | 0.94 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL9498967 | 0.94 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL20343290 | 0.94 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7902520 | 0.94 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7509846 | 0.94 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6462682 | 0.94 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| EP-0220254-B1 | BENZONITRILES | MERCK PATENT GmbH (DE) | 1990-10-24 | — | — | EP | disclosed |
| WO-1990004622-A1 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-05-03 | — | — | WO | disclosed |
| US-4751017-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-06-14 | — | — | US | disclosed |
| US-4715984-A | DIELECTRICS FOR ELECTROOPTICAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-12-29 | — | — | US | disclosed |
| EP-0220254-A1 | BENZONITRILES. | MERCK PATENT GMBH (DE) | 1987-05-06 | — | — | EP | disclosed |
| US-4630896-A | Benzonitriles | HOFFMANN-LA ROCHE INC. (US) | 1986-12-23 | — | — | US | disclosed |
| WO-1986006372-A1 | BENZONITRILE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-11-06 | — | — | WO | disclosed |
| EP-0129177-A2 | Nematic benzonitriles | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-12-27 | — | — | EP | disclosed |