⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628830 | 1.00 | — | — | |
| SCHEMBL4892023 | 0.88 | — | — | |
| SCHEMBL14385517 | 0.86 | — | — | |
| SCHEMBL11853458 | 0.86 | CA1 (0.34) | — | |
| SCHEMBL19934202 | 0.84 | — | — | |
| SCHEMBL18923134 | 0.84 | — | — | |
| SCHEMBL7910927 | 0.84 | — | — | |
| SCHEMBL17540096 | 0.84 | — | — | |
| SCHEMBL24742716 | 0.80 | — | — | |
| SCHEMBL21828098 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655944-B2 | Inhibitors of hepatitis C virus | GILEAD SCIENCES, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| WO-2014177038-A1 | AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-11-06 | — | — | WO | disclosed |
| US-8541617-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8541617-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-09-24 | — | — | US | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-8039623-B2 | Peptidomimetics compound; viricides; interference in life cycle og hepatitis c virus | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-10-18 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| EP-1606254-B1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-7273885-B2 | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-09-25 | — | — | US | disclosed |
| WO-2007096058-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-08-30 | — | — | WO | disclosed |
| US-20070161789-A1 | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease | VERTEX PHARMACEUTICALS INCORPORATED | 2007-07-12 | — | — | US | disclosed |
| US-7241796-B2 | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease | VERTEX PHARMACEUTICALS INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-7208600-B2 | Inhibitors of serine proteases, particularly HCV NS3-NS4A proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-04-24 | — | — | US | disclosed |
| US-20070032526-A1 | Cyclic derivatives as modulators of chemokine receptor activity | CARTER PEROY H | 2007-02-08 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| US-7163937-B2 | Cyclic derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-16 | — | — | US | disclosed |
| US-6201137-B1 | CONTACTING CRUDE TETRAHYDROFURAN WITH MINERAL ACID SELECTED FROM THE GROUP CONSISTING OF NITRIC ACID, SULFURIC ACID, AND PHOSPHORIC ACID, THEN INSTANTLY DISTILLATING | HODOGAYA CHEMICAL CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |