⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492 | 0.79 | KDM4E (0.39) | — | |
| SCHEMBL22924 | 0.77 | KDM4E (0.37) | — | |
| SCHEMBL27916861 | 0.77 | KDM4E (0.37) | — | |
| SCHEMBL4356890 | 0.77 | KDM4E (0.37) | — | |
| SCHEMBL1652589 | 0.77 | KDM4E (0.37) | — | |
| Ammonia Solution, Strong SCHEMBL536032 | 0.77 | KDM4E (0.37) | — | |
| SCHEMBL30699345 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL4687605 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL30154994 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL2469007 | 0.73 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6190904-B1 | INDUSTRIAL PROCESS FOR CLEANING A HARD SURFACE WITH A MODIFIED SUBTILISIN PROTEASE HAVING SUBSTITUTION OF ARGININE FOR THE AMINO ACIDS AT SPECIFIED POSITIONS IN A SEQUENCE; ALSO USE FOR DEHAIRING HIDES IN MANUFACTURE OF LEATHER | GENECOR INTERNATIONAL, INC. | 2001-02-20 | — | — | US | disclosed |