Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610873 | 0.82 | CYP19A1 (0.53) | FFAR1AKR1B1CYP19A1FFAR4MAPT | |
| SCHEMBL2692033 | 0.81 | CYP19A1 (0.50) | CYP1A2SMN1; SMN2CYP2C19CYP19A1 | |
| SCHEMBL27331545 | 0.81 | CYP19A1 (0.55) | CYP1A2FFAR1AKR1B1CYP2C19CYP19A1 | |
| SCHEMBL4253894 | 0.80 | CYP19A1 (0.49) | CYP19A1 | |
| SCHEMBL18338672 | 0.79 | TSHR (0.50) | CYP19A1 | |
| SCHEMBL4256526 | 0.79 | TSHR (0.50) | CYP19A1 | |
| SCHEMBL11026315 | 0.79 | TSHR (0.50) | CYP19A1 | |
| SCHEMBL10718053 | 0.79 | TSHR (0.50) | CYP19A1 | |
| SCHEMBL3910779 | 0.79 | CYP19A1 (0.56) | CYP1A2FFAR1AKR1B1CYP2C19CYP19A1 | |
| SCHEMBL98234 | 0.78 | CYP1A2 (0.56) | CYP1A2FFAR1HDAC3MAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6190841-B1 | ACID GENERATOR WHICH GENERATES AN ACID WHEN IRRADIATED WITH ACTINIC RADIATION, AND COMPOUND CONTAINING CARBOXYL GROUPS, WHICH CAN DECOMPOSE UPON DECARBOXYLATION | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-20 | — | — | US | disclosed |