Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900856 | 0.76 | PARP15 (0.52) | PARP15PARP10PARP3 | |
| SCHEMBL7907779 | 0.75 | — | — | |
| SCHEMBL7907773 | 0.75 | — | — | |
| SCHEMBL5326831 | 0.73 | IDH1 (0.58) | MAPK1 | |
| SCHEMBL7901074 | 0.73 | APP (0.57) | PARP15PARP10PARP3F2 | |
| SCHEMBL30900828 | 0.70 | KDM1A (0.54) | MAPK1 | |
| SCHEMBL9585819 | 0.70 | PARP15 (0.50) | PARP15PARP10PARP3 | |
| SCHEMBL6068182 | 0.70 | KDM1A (0.54) | MAPK1 | |
| SCHEMBL7908840 | 0.70 | — | — | |
| SCHEMBL7900857 | 0.70 | PARP15 (0.49) | PARP15PARP10PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |