Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.62 |
| ▸ | PI4KA | P42356 | 3/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807259 | 0.86 | PIK3CG (0.83) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL807260 | 0.85 | PIK3CA (0.58) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL10277636 | 0.79 | PIK3CG (0.84) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL807249 | 0.77 | PIK3CG (0.86) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL807085 | 0.77 | PIK3CG (1.00) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL790675 | 0.76 | PIK3CA (0.69) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL14247434 | 0.74 | PIK3CG (0.70) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL789471 | 0.74 | PIK3CG (0.81) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL807088 | 0.74 | PIK3CG (0.82) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD | |
| SCHEMBL14315224 | 0.73 | PIK3CG (0.75) | PIK3CGPI4KAPIK3CAPIK3R1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |