Acetic Acid

Acetic Acid

SCHEMBL7901393

CC(=O)[O-].CC(=O)[O-].CC(=O)[O-].C[Si](C)(C)CCCNCCN.[Na+].[Na+].[Na+]

nearest known ligand 0.42

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 4/20 0.42
CA12 O43570 4/20 0.39
CA6 P23280 4/20 0.39
CA7 P43166 4/20 0.39
CA9 Q16790 4/20 0.39
CA14 Q9ULX7 4/20 0.39
CA5B Q9Y2D0 4/20 0.39
CA2 P00918 3/20 0.39
CA4 P22748 3/20 0.39
CA5A P35218 3/20 0.39
CA3 P07451 2/20 0.39
MEN1 O00255 2/20 0.37
RECQL P46063 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CA1 P00915 2/20 0.36
ALOX15 P16050 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27218925 0.89 PAOX (0.44) PAOXCA12CA6CA7CA9
Acetic Acid SCHEMBL29259811 0.84 CA12 (0.53) PAOXCA12CA6CA7CA9
Acetic Acid SCHEMBL9110421 0.84 CA12 (0.53) PAOXCA12CA6CA7CA9
Acetic Acid SCHEMBL155357 0.84 CA12 (0.53) PAOXCA12CA6CA7CA9
Acetic Acid SCHEMBL9568670 0.84 CA12 (0.53) PAOXCA12CA6CA7CA9
SCHEMBL5577158 0.84 CA12 (0.55) PAOXCA12CA6CA7CA9
Acetic Acid SCHEMBL15453590 0.83 PAOX (0.38) PAOXCA12CA6CA7CA9
Acetic Acid SCHEMBL9267542 0.82 CA12 (0.50) PAOXCA12CA6CA7CA9
SCHEMBL1270857 0.82 CA12 (0.55) CA12CA6CA7CA9CA14
Acetic Acid SCHEMBL9128649 0.82 CA12 (0.50) PAOXCA12CA6CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6187491-B1 ELEMENT COMPRISING AN ELECTROCONDUCTIVE LAYER, PHOTOCONDUCTOR LAYER, PRIMER LAYER AND A SOLID POLYMER ELECTROLYTE LAYER COMPOSED OF A POLYSILSESQUIOXANE COMPLEXED WITH A CHARGE CARRIER AND INCLUDING AN ARYL TERTIARY AMINE EASTMAN KODAK COMPANY 2001-02-13 US disclosed