⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971556 | 1.00 | — | — | |
| SCHEMBL7903270 | 1.00 | — | — | |
| SCHEMBL31756922 | 0.86 | — | — | |
| SCHEMBL18227509 | 0.84 | — | — | |
| SCHEMBL18227510 | 0.84 | — | — | |
| SCHEMBL14639046 | 0.80 | — | — | |
| SCHEMBL9608918 | 0.78 | — | — | |
| SCHEMBL1875223 | 0.78 | — | — | |
| SCHEMBL167570 | 0.78 | — | — | |
| SCHEMBL7161641 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194576-B1 | COUPLING PURINE OR PYRIMIDINE BASE WITH NUCLEOTIDE ANALOG PHOSPHONATE COMPOUND | BIOCHEM PHARMA, INC. (CA) | 2001-02-27 | — | — | US | disclosed |
| US-6127540-A | NUCLEOTIDE ANALOGS MADE BY COUPLING A PURINE OR PYRIMIDINE NUCLEOTIDE BASE OR ANALOGUE THEREOF WITH A 2-(PHOSPHONATE)FURAN OR 2-(PHOSPHONATE)THIOFURAN OF GIVEN FORMULA; USE AS NON-TOXIC ANTIVIRAL DRUGS | BIOCHEM PHARMA, INC. (CA) | 2000-10-03 | — | — | US | disclosed |
| US-6005107-A | Antiviral compounds | BIOCHEM PHARMA, INC. (CA) | 1999-12-21 | — | — | US | disclosed |
| US-5955610-A | COUPLING PHOSPHONATE INTERMEDIATE WITH PURINE OR PYRIMIDINE NUCLEOTIDE BASE | BIOCHEM PHARMA, INC. (CA) | 1999-09-21 | — | — | US | disclosed |
| US-5789394-A | VIRICIDES FOR CYTOMEGALOVIRUS USING NUCLEOTIDES | NGUYEN-BA NGHE (CA) | 1998-08-04 | — | — | US | disclosed |