Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.45 |
| ▸ | CDK9 | P50750 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788485 | 0.78 | CCNT1 (0.51) | CCNT1CDK9DRD2DRD3HTR2A | |
| SCHEMBL2467564 | 0.77 | HTR2A (0.49) | CCNT1CDK9DRD2DRD3HTR2A | |
| SCHEMBL2789340 | 0.74 | CCNT1 (0.50) | CCNT1CDK9KCNH2 | |
| SCHEMBL2789642 | 0.73 | HTR2A (0.53) | CCNT1CDK9DRD2HTR2AHTR2C | |
| SCHEMBL25361747 | 0.73 | CCNT1 (0.37) | CCNT1CDK9DAODDO | |
| SCHEMBL26025637 | 0.73 | CCNT1 (0.37) | CCNT1CDK9DAODDO | |
| Bromide SCHEMBL7865092 | 0.72 | HRH4 (0.51) | CCNT1CDK9HRH4 | |
| SCHEMBL2005837 | 0.72 | CCNT1 (0.48) | CCNT1CDK9 | |
| SCHEMBL2013169 | 0.72 | CCNT1 (0.48) | CCNT1CDK9 | |
| SCHEMBL2008646 | 0.72 | CCNT1 (0.48) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |